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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: F13A_HUMAN




USC-OGP 2-DE database:  F13A_HUMAN


F13A_HUMAN


General information about the entry
View entry in simple text format
Entry nameF13A_HUMAN
Primary accession numberP00488
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Coagulation factor XIII A chain; Short=Coagulation factor XIIIa; EC=2.3.2.13 {ECO:0000269|PubMed:27363989}; AltName: Full=Protein-glutamine gamma-glutamyltransferase A chain; AltName: Full=Transglutaminase A chain; Flags: Precursor;.
Gene nameName=F13A1
Synonyms=F13A
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_4-5 {PLATELET 4-5}
Homo sapiens (Human)
PLATELET_4-5
  map experimental info
 
PLATELET_4-5

MAP LOCATIONS:
pI=4.86; Mw=62526
pI=4.96; Mw=18897



PLATELET_4-7 {PLATELET 4-7}
Homo sapiens (Human)
PLATELET_4-7
  map experimental info
 
PLATELET_4-7

MAP LOCATIONS:
pI=5.72; Mw=87145
pI=5.65; Mw=86228



PLATELET_5-6 {PLATELET 5-6}
Homo sapiens (Human)
PLATELET_5-6
  map experimental info
 
PLATELET_5-6

MAP LOCATIONS:
pI=5.69; Mw=92858
pI=5.66; Mw=90293
pI=5.73; Mw=87799



PLATELET_6-11 {PLATELET 6-11}
Homo sapiens (Human)
PLATELET_6-11
  map experimental info
 
PLATELET_6-11

MAP LOCATIONS:
pI=5.95; Mw=80837

Cross-references
UniProtKB/Swiss-ProtP00488; F13A_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameF13A_HUMAN
Primary accession numberP00488
Secondary accession number(s) Q59HA7 Q8N6X2 Q96P24 Q9BX29
Sequence was last modified on January 23, 2007 (version 4)
Annotations were last modified on March 15, 2017 (version 208)
Name and origin of the protein
DescriptionRecName: Full=Coagulation factor XIII A chain; Short=Coagulation factor XIIIa; EC=2.3.2.13 {ECO:0000269|PubMed:27363989}; AltName: Full=Protein-glutamine gamma-glutamyltransferase A chain; AltName: Full=Transglutaminase A chain; Flags: Precursor;
Gene nameName=F13A1
Synonyms=F13A
Encoded onName=F13A1; Synonyms=F13A
Keywords3D-structure; Acetylation; Acyltransferase; Blood coagulation; Calcium; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Glycoprotein; Hemostasis; Metal-binding; Polymorphism; Reference proteome; Secreted; Transferase; Zymogen.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM14539; AAA52489.1; ALT_INIT; mRNA
EMBLM14354; AAA52488.1; -; mRNA
EMBLM22001; AAA52415.1; -; Genomic_DNA
EMBLM21987; AAA52415.1; JOINED; Genomic_DNA
EMBLM21988; AAA52415.1; JOINED; Genomic_DNA
EMBLM21989; AAA52415.1; JOINED; Genomic_DNA
EMBLM21990; AAA52415.1; JOINED; Genomic_DNA
EMBLM21991; AAA52415.1; JOINED; Genomic_DNA
EMBLM21992; AAA52415.1; JOINED; Genomic_DNA
EMBLM21993; AAA52415.1; JOINED; Genomic_DNA
EMBLM21995; AAA52415.1; JOINED; Genomic_DNA
EMBLM21996; AAA52415.1; JOINED; Genomic_DNA
EMBLM21997; AAA52415.1; JOINED; Genomic_DNA
EMBLM21998; AAA52415.1; JOINED; Genomic_DNA
EMBLM21999; AAA52415.1; JOINED; Genomic_DNA
EMBLM22000; AAA52415.1; JOINED; Genomic_DNA
EMBLAB208852; BAD92089.1; ALT_INIT; mRNA
EMBLAF418272; AAL12161.1; -; Genomic_DNA
EMBLAL157775; CAC36886.3; -; Genomic_DNA
EMBLAL133326; CAC36886.3; JOINED; Genomic_DNA
EMBLAL391420; CAC36886.3; JOINED; Genomic_DNA
EMBLAL391420; CAI39797.2; -; Genomic_DNA
EMBLAL133326; CAI39797.2; JOINED; Genomic_DNA
EMBLAL157775; CAI39797.2; JOINED; Genomic_DNA
EMBLAL133326; CAO03607.1; -; Genomic_DNA
EMBLAL157775; CAO03607.1; JOINED; Genomic_DNA
EMBLAL391420; CAO03607.1; JOINED; Genomic_DNA
EMBLBC027963; AAH27963.1; -; mRNA
CCDSCCDS4496.1; -; .
PIRA35583; EKHUX; .
RefSeqNP_000120.2; NM_000129.3; .
UniGeneHs.335513; -; .
PDB1EVU; X-ray; 2.01 A; A/B=2-732
PDB1EX0; X-ray; 2.00 A; A/B=2-732
PDB1F13; X-ray; 2.10 A; A/B=2-732
PDB1FIE; X-ray; 2.50 A; A/B=2-732
PDB1GGT; X-ray; 2.65 A; A/B=2-732
PDB1GGU; X-ray; 2.10 A; A/B=2-732
PDB1GGY; X-ray; 2.50 A; A/B=2-732
PDB1QRK; X-ray; 2.50 A; A/B=2-732
PDB4KTY; X-ray; 1.98 A; A/B=2-732
PDBsum1EVU; -; .
PDBsum1EX0; -; .
PDBsum1F13; -; .
PDBsum1FIE; -; .
PDBsum1GGT; -; .
PDBsum1GGU; -; .
PDBsum1GGY; -; .
PDBsum1QRK; -; .
PDBsum4KTY; -; .
ProteinModelPortalP00488; -; .
SMRP00488; -; .
BioGrid108460; 11; .
DIPDIP-377N; -; .
IntActP00488; 9; .
MINTMINT-7966415; -; .
STRING9606.ENSP00000264870; -; .
BindingDBP00488; -; .
ChEMBLCHEMBL4530; -; .
DrugBankDB00130; L-Glutamine; .
DrugBankDB02340; N-Acetyl-Serine; .
iPTMnetP00488; -; .
PhosphoSitePlusP00488; -; .
BioMutaF13A1; -; .
DMDM119720; -; .
OGPP00488; -; .
MaxQBP00488; -; .
PaxDbP00488; -; .
PeptideAtlasP00488; -; .
PRIDEP00488; -; .
TopDownProteomicsP00488; -; .
DNASU2162; -; .
EnsemblENST00000264870; ENSP00000264870; ENSG00000124491; .
GeneID2162; -; .
KEGGhsa:2162; -; .
UCSCuc003mwv.4; human; .
CTD2162; -; .
DisGeNET2162; -; .
GeneCardsF13A1; -; .
HGNCHGNC:3531; F13A1; .
HPACAB002155; -; .
HPAHPA001804; -; .
MalaCardsF13A1; -; .
MIM134570; gene+phenotype; .
MIM613225; phenotype; .
neXtProtNX_P00488; -; .
Orphanet331; Congenital factor XIII deficiency; .
PharmGKBPA162; -; .
eggNOGENOG410IFMV; Eukaryota; .
eggNOGENOG410XQEZ; LUCA; .
HOGENOMHOG000231695; -; .
HOVERGENHBG004342; -; .
InParanoidP00488; -; .
KOK03917; -; .
OrthoDBEOG091G030K; -; .
PhylomeDBP00488; -; .
TreeFamTF324278; -; .
ReactomeR-HSA-114608; Platelet degranulation; .
ReactomeR-HSA-140875; Common Pathway of Fibrin Clot Formation; .
ReactomeR-HSA-6785807; Interleukin-4 and 13 signaling; .
ChiTaRSF13A1; human; .
EvolutionaryTraceP00488; -; .
GeneWikiCoagulation_factor_XIII; _A1_polypeptide; -; .
GenomeRNAi2162; -; .
PMAP-CutDBP00488; -; .
PROPR:P00488; -; .
ProteomesUP000005640; Chromosome 6; .
BgeeENSG00000124491; -; .
CleanExHS_F13A1; -; .
ExpressionAtlasP00488; baseline and differential; .
GenevisibleP00488; HS; .
GOGO:0072562; C:blood microparticle; IDA:UniProtKB; .
GOGO:0005576; C:extracellular region; TAS:Reactome; .
GOGO:0031093; C:platelet alpha granule lumen; TAS:Reactome; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IDA:UniProtKB; .
GOGO:0007596; P:blood coagulation; TAS:Reactome; .
GOGO:0072378; P:blood coagulation; fibrin clot formation; IDA:UniProtKB
GOGO:0018149; P:peptide cross-linking; IDA:UniProtKB; .
GOGO:0002576; P:platelet degranulation; TAS:Reactome; .
Gene3D2.60.40.10; -; 3; .
Gene3D3.90.260.10; -; 1; .
InterProIPR023608; Gln_gamma-glutamylTfrase_euk; .
InterProIPR013783; Ig-like_fold; .
InterProIPR014756; Ig_E-set; .
InterProIPR002931; Transglutaminase-like; .
InterProIPR013808; Transglutaminase_AS; .
InterProIPR008958; Transglutaminase_C; .
InterProIPR001102; Transglutaminase_N; .
PANTHERPTHR11590; PTHR11590; 1; .
PfamPF00927; Transglut_C; 2; .
PfamPF01841; Transglut_core; 1; .
PfamPF00868; Transglut_N; 1; .
PIRSFPIRSF000459; TGM_EBP42; 1; .
SMARTSM00460; TGc; 1; .
SUPFAMSSF49309; SSF49309; 2; .
SUPFAMSSF81296; SSF81296; 1; .
PROSITEPS00547; TRANSGLUTAMINASES; 1; .



USC-OGP 2-DE database image


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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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